New COG/SIOP harmonized risk groups (AREN0534, UMBRELLA):

: This "rule of thumb" notes that roughly 10% of cases are bilateral (affecting both kidneys), 10% have unfavorable histology, and 10% present with pulmonary metastases. National Institutes of Health (.gov) Clinical Presentation Patients often present with an asymptomatic, firm abdominal mass . Other common symptoms include: Slideshare evidence based management of wilms tumor - AROI

Word count: ~1,450. Suitable for a 30-45 minute presentation, expandable to 2 hours with case discussions and references.

The prognosis for children with Wilms tumor is generally good, with a 5-year survival rate of about 90%. However, the prognosis depends on the stage of the disease at diagnosis and the response to treatment.