For ADS (E36/E34) communication, 6.4.3 requires a true serial port (RS232) with a physical ADS interface (like the "Tiny ADS" or "BMDiagnostics ADS"). USB-to-serial adapters do not correctly handle the battery voltage detection required for ADS init.
6.4.3 still heavily relies on Serial or STD:OBD definitions, not purely the Remote interface of newer versions. ediabas 6.4.3