Understanding the "flight zone" of cattle, a concept popularized by Dr. Temple Grandin, has led to the design of more humane handling facilities. This reduces animal distress and improves meat quality and handler safety.

A classic example is the "pill war." If a vet sends a fearful cat home with a bitter pill and instructions to force it down the throat, the cat may learn to hide or scratch the owner. The owner stops giving the medication.

Key organizations and journals lead research and set standards for the field:

The impact of stress on physical health is well-documented in human medicine, and it is equally relevant in veterinary science. Fear and anxiety trigger the release of cortisol and catecholamines, which can have cascading effects on the body.