Corel frequently releases updates and patches to fix bugs and address security vulnerabilities in the .CDR file format. A portable version is generally static; it cannot be updated, leaving the user vulnerable to exploits that have been patched in the official release.
For professional use, always purchase a legitimate license from Corel/Alludo and install it properly. For casual or portable needs, use open-source alternatives like Inkscape or GIMP. Corel 2022 Portable